A Reuters reporter saw a vehicle that was carrying killed and injured security personnel in the area close to those, where police have been conducting an operation against alcohol and drug dealers.
According to the reports, police officials have not commented on the incident so far.
A regional affiliate of the Islamic State militant group claimed responsibility for the attack, saying it had targeted the police.
More details are awaited.
Afghanistan's Interior Ministry spokesman says a suicide bomber has killed six policemen after exploding his devise amid a group of security officials monitoring protests by shopkeepers in eastern Kabul.
No individual or group has yet claimed responsibility behind the attack.
Kabul police spokesman Basir Mujahid said at least five police had been killed.
Photo Ambulances and security forces converged near the scene of a suicide bombing in Kabul, Afghanistan, on Thursday.
Either way, the attack was yet another sign of rising violence and insecurity in Kabul.
The capital has become one of the deadliest places in war-torn Afghanistan for civilians in recent months, as the Taliban step up their attacks and Daesh seeks to expand its presence in the country.
The casualties have been confirmed by Kabul Police.
Despite the increased security measures militants continue to carry out attacks.