Guardiola told reporters on Tuesday that Silva is doubt for Sunday's Manchester derby against United, but refused to specify the midfielder's problem, simply describing the issue as "something".
"It was similar to the last few games, in the second half I thought we would score".
Shakhtar are second in the group on nine points and need to avoid losing, besides that being their responsibility, since Napoli can leapfrog them into second if they beat Feyenoord and Man City win.
However, according to Sky Italia the Catalan has sent an SMS message to Napoli boss Maurizio Sarri, promising him that City will give their 'maximum effort' to beat Shakhtar and make it six wins out of six in Group F.
Fernandes is a different prospect entirely and it will be interesting to see how many more chances he gets in the weeks ahead. He is injured but he will play for sure.
At the back, many are calling for Tosin Adarabioyo to start this one, which makes a lot of sense.
Pep Guardiola said in his pre-match presser that he wants his team to win this game, but that doesn't mean he'll go with a really strong team.
Silva, who last month signed a one-year contract extension until 2020, has been sensational in that run, scoring twice and laying on eight assists as Guardiola's side have set about dismantling Premier League opposition at will.
Shakhtar's motivation was obvious and in Brazilians Taison and Bernard they boasted plenty of attacking drive. Benjamin Mendy is the club's only long-term absentee as he continues to recover from an anterior cruciate ligament injury.
Manchester City's 13 goals in the Champions League this season have either been scored in open play (8) or from a corner kick (5, the most in 2017/18). "You want the truth", the United boss said, laughing.
Toure feels the team is making considerable strides under Pep Guardiola and is eager to challenge for Champions League glory again.
Fonseca said: 'We are not going to follow the game in Rotterdam.
Unsurprisingly, ever since then, he's found first-team football hard to come by and has even been left out of matchday squads by Mauricio Pochettino.
Nicolas Otamendi had converted substitute Gabriel Jesus's cross in the 57th minute to equalise, after defender Angelo Ogbonna had headed West Ham into the lead.