Lopetegui has therefore decided to recall 35-year-old Villa even though the New York City striker has not played a game for Spain since the 2014 World Cup.
Brahim has represented Spain at Under-17 and Under-19 level and impressed on City's pre-season tour of America with goals against Real Madrid and Tottenham, winning a spot in Guardiola's first-team squad.
Villa is Spain's all-time top scorer, with 59 goals in 97 appearances for La Roja. The Italian has been Villa's equal in terms of his importance to his MLS club. "After that, we show that we can win to everyone, and we can lose to everyone".
"It will be a beautiful game", Lopetegui said. Villa had all but given up hope on returning to the international fold, but the chance to play for his country again is a dream come true. When you see the games, when you see the league, when you see everything around the MLS, you can enjoy a lot because it is great.
Villa won the 2010 World Cup and 2008 European Championship with Spain, and he's been playing in MLS for the past three years after leaving Atletico Madrid.
When both Giovinco and NYCFC midfielder Andrea Pirlo were left off Italy's provisional roster for Euro 2016, then Italy manager Antonio Conte famously said, "When you make a certain choice and go to play in certain leagues, you do so taking it into account that they could pay the consequences from a footballing viewpoint". "I mean Neymar is one of the greatest players in the world - everybody knows".
"We know Suso well from the youth sides", Lopetegui said.