United have invested heavily on the signings of Romelu Lukaku, Nemanja Matic and Victor Lindelof in the transfer window, while champions Chelsea, Manchester City, Liverpool and Arsenal have also spent large sums.
And although he admits Mourinho and Conte are different, he is desperate for more success in West London under the former Juventus chief.
After surrendering 39 goals last season, Man City made it a top priority to address the backend this off-season, and they did exactly that with the acquisitions of Ederson Moraes in goal and defenders Kyle Walker and Danilo.
Chelsea lost only five games last season in a 30-win campaign, winning the league title with a 30-5-3 record.
Chelsea manager Antonio Conte looked frustrated on the touchline at Wembley and with good reason.
Townsend feels the Amex Stadium outfit have every chance of a long-term future in the Premier League should they beat the drop this time.
Having experienced nearly three months of transfer speculation and deals featuring absurd sums of money, ridiculous rumours and unashamed greed, it is almost a relief that the Premier League finally kicks off this weekend. Following his operation, doctors commented on their surprise at the strength and speed of his recover, given the Swede's age.
It will be a tough season ahead, but I have a feeling Brighton will survive, probably by the skin of their teeth.
Managing expectations can be a tricky thing in the world of professional football. Striker Romelu Lukaku cost at least 75 million pounds, while Mourinho offloaded captain Wayne Rooney in the opposite direction to Everton.
But City, boosted by a £200million summer spending spree, were ruthless in overcoming the stubborn Seagulls, with Sergio Aguero's goal after 70 minutes followed by Lewis Dunk's own goal. Losing Sanchez would jeopardise Arsenal's attempt to rejoin the elite. And now you are looking at Marcus Rashford, Jesse Lingard, Juan Mata, Anthony Martial and Henrikh Mkhitaryan, and you're thinking the rest of the team picks itself.
Mourinho told a news conference on Friday: "We have 25 percent left which means one of four - we got a central defender that can play many other positions which is very important".
Hughton, who will assess Chelsea loanee Izzy Brown's hamstring injury on Sunday, bemoaned his side relinquishing possession too easily, but felt there were "more positives than negatives".
His innate poacher instincts will come in handy for a side who have had the poorest conversion rate among the top seven sides and could prove to be the difference between a battle for fourth and a push for the title.
The English Premier League is back for its 26th edition, a milestone year for England's top league.
Sofiane Feghouli, Cheikhou Kouyate, Diafra Sakho, Andy Carroll, Manuel Lanzini and Michail Antonio are all out of the trip to Manchester United.
The Manchester boss has resided in the hotel ever since his arrival last summer and it would seem he has grown rather fond of the place as he has pencilled himself in for the whole of the upcoming season as well.