The Blues couldn't have played a worse first half of football, falling behind to Burnley 3-0 before getting up off the canvas and clawing two back in the second half to finish the match 3-2.
And finally, Ronald Koeman and his band of new Everton signing's host Stoke City on Merseyside, looking to get off to a good start in their pursuit of breaking into the top six.
That was an honour that fell to Sam Vokes with his late goal rush and after adding a double at the Bridge he now has seven goals in his last six Premier League games.
Antonio Conte said he saw two different sides of his Chelsea team in their 3-2 defeat by Burnley. "After the red card we lost our heads, conceded two goals and then it's very difficult to change the final result".
"I have to try to adapt a new system and to anticipate playing with nine or 10 men in the next game".
Chelsea did their best to launch a positive response, but the Blues were struggling, and Burnley incredibly doubled their lead in the 39th minute when Stephen Ward broke into the home side's box before finding the top corner with a stunning strike.
"But our first half, we kept losing our heads".
There have been times when Burnley have been too honest. We'll never know, but it's the kind of trick other Premier League sides pull on a regular basis, and falls firmly into the gamesmanship category.
"We controlled the counter-attacks and we didn't concede one chance", Guardiola told BBC Sport. We must have the right experience to face this situation.
"We tried until the end to reach a good result against Burnley".
Assisted by a woeful home defence, the underdogs were out of sight by half-time and although Chelsea dominated the second-half with Â£58million striker Alvaro Morata on target, they had left themselves too much ground to claw back. This time it was Defour who curled the ball into the area.
Watford twice went in front through Stefano Okaka and Abdoulaye Doucoure, but Liverpool equalised each time via Sadio Mane and Roberto Firmino, who then teed up new boy Mohamed Salah to put the visitors 3-2 up. I want to win.
West Brom, fresh off handing Tony Pulis a one-year contract extension, host Bournemouth at the Hawthorns, with Jay Rodriguez looking to hit the ground running following an injury-hit few years at Southampton.
43' - GOAL! Chelsea 0-3 Burnley.